Propel your investigations in arylcyclohexylamine chemistry and NMDA receptor pharmacology with our premium 2F-DCK (2-Fluorodeschloroketamine) 100mg pellets, a fluorinated analog of deschloroketamine engineered for precise studies of dissociative mechanisms and structural modifications. This novel research chemical facilitates detailed explorations of receptor binding affinities and metabolic pathways, providing the consistency essential for reproducible outcomes in controlled laboratory environments. Our 2F-DCK for research delivers 99%+ purity via stringent refinement processes, eliminating contaminants that might distort results in analytical assays like LC-MS or electrophysiological recordings, positioning it as an indispensable tool for scientists advancing knowledge in neuropharmacology.

Physical and Chemical Properties:

• Appearance: White to off-white crystalline powder or compressed into uniform 100mg pellets for accurate dosing
• Molecular Formula: C13H16FNO
• Molecular Weight: 221.27 g/mol
• Solubility: Soluble in DMSO (>50 mg/mL) and ethanol; moderately soluble in water as HCl salt (~20 mg/mL at pH 5)
• Melting Point: 92-96°C (free base); 178-182°C (HCl salt)
• Purity Level: 99.5%+ authenticated by HPLC and HRMS
• CAS Number: 111982-50-4 (free base); 111982-49-1 (HCl salt)
• Storage: Sealed in amber vials under inert atmosphere at -20°C to preserve integrity

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Introduction

In the intricate domain of dissociative anesthetics and novel psychoactive substance analogs, 2F-DCK (2-Fluorodeschloroketamine) stands out as a sophisticated research entity, enabling scientists to unravel the subtleties of arylcyclohexylamine pharmacodynamics. This ortho-fluorinated derivative of ketamine, characterized by its cyclohexanone core adorned with a 2-fluorophenyl and N-methylamino group, has risen in prominence since its emergence around 2016 as a tool for probing NMDA antagonism and stereochemical influences. Its structural deviation from ketamine—replacing chlorine with fluorine—offers a unique lens for examining lipophilicity, potency, and biotransformation in preclinical models.

As a foremost authority in analytical research chemicals, we furnish 99% pure 2F-DCK in convenient 100mg pellets, calibrated to the rigorous benchmarks of international laboratories and ensuring your protocols yield unequivocal, publication-ready data. Weary of subpar vendors with erratic purity or sluggish logistics? When you order 2F-DCK powder online, our optimized system delivers elite-grade material with velocity and veiled transport, catalyzing your inquiries into receptor kinetics or synthetic derivatization. From dissecting hallucinogenic thresholds via behavioral assays to mapping CYP-mediated metabolism, our purchase 2F-DCK research chemical empowers paradigm shifts. Step into the vanguard of chemical neuroscience—2F-DCK is your conduit to pioneering revelations.

Key Features & Benefits

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Product Specifications

Our ethos of analytical supremacy manifests in the exacting specifications of 2F-DCK, harmonized with global edicts like those from the International Conference on Harmonisation (ICH). These particulars expedite judicious incorporation into your regimens, spanning fabrication to validation. Survey the empirical dossier:

Property	Specification
Molecular Structure	2-(2-Fluorophenyl)-2-(methylamino)cyclohexan-1-one (arylcyclohexylamine scaffold)
Purity	≥99.5% (HPLC, free base equivalent)
Particle Size	10-50 μm (pellet form: 100mg uniform compression for dosing precision)
Density	1.12 g/cm³
UV Absorption	λ_max 262 nm (characteristic aryl ketone band)
Stability	Stable 18-24 months refrigerated; susceptible to photodegradation
Packaging Options	100mg pellets in blister packs; bulk 500mg/1g vials

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Applications & Usage

2F-DCK functions as an adept probe within the pantheon of ketamine analogs, notably for interrogating fluorine’s ramifications on dissociative pharmacophores. In neuropharmacology, it underpins assays of NMDA receptor occlusion and hallucinatory phenomenology, consonant with directives from the European Monitoring Centre for Drugs and Drug Addiction (EMCDDA). Forensic toxicologists harness 2F-DCK for research in HRMS-based metabolite elucidation, as chronicled in Drug Testing and Analysis, to fortify detection schemas for novel psychoactive substances (NPS).

Organic chemists prize it for fluorination cascade explorations, whereas biochemists chart its CYP2B6/CYP3A4-mediated N-demethylation to nor-2F-DCK. For efficacious deployment, dissolve pellets in DMSO via ultrasonication to 10 mM reservoirs, thence titrate into physiological media; utilize chiral separations for enantiomeric discernment where pertinent. Our iteration thrives in these spheres, proffering the constancy vital for subsidized initiatives or adjudicated treatises. Exclusively for in vitro and ex vivo applications, invariably synchronize with institutional safeguards and SDS imperatives.

Purity & Testing

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Safety & Handling Guidelines

Laboratory prudence is sacrosanct when interfacing with arylcyclohexylamines such as 2F-DCK, and we proffer meticulous directives to attenuate latent perils. As pelletized or powdered material, it necessitates manipulation within a ventilated enclosure with particulate filtration, attired in requisite PPE: N95 respirators, solvent-proof gauntlets, and ocular barriers to preclude inhalation or transdermal ingress.

Upon exposure, irrigate zones lavishly and invoke activated charcoal for suspected intake, pursued by erudite appraisal. Sustain in desiccated, inert milieus to thwart hydrolytic vicissitudes, and inter via sanctioned thermal degradation per EPA analogs. Designated purely for research—proscribed for human/animal ingress, diagnostica, or extraneous intents. Qualified procurers (18+) shoulder accountability for statutory conformity; dereliction abrogates indemnities and exacts unmitigated onus.

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Legal & Safety Disclaimer

2F-DCK is tendered solely for corroborated laboratory research and is inadmissible for human or veterinary imbibition, remedial probation, or consumptive ventures. Acquirers must surmount 18 annums, ratifying harmony with all apposite local, federal, and supranational decrees on analytical essences. We repudiate onus for anomalous exertion, with procurers indemnifying contra resultant averments. Invoke juridical advisement for locale-customized glosses, and peruse the adjunct SDS for plenary hazard and palliation erudition.

FAQ

What is 2F-DCK Used for in Research?

2F-DCK (2-Fluorodeschloroketamine) is instrumental in 2F-DCK for research, facilitating interrogations of fluorination’s imprint on ketamine scaffolds, encompassing NMDA blockade and metabolic cascades. It sustains in vitro receptor assays and NPS forensic cataloging, attuned to EMCDDA rubrics, devoid of non-laboratory extrapolations.

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As an analytical reagent, 99% pure 2F-DCK is feasible for erudite procurement in myriad realms when circumscribed to accredited lab precincts. Normative divergence prevails; we tender export facilitation to underpin licit purchase 2F-DCK research chemical liaisons—diligence on edicts is obligatory.

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We profess ≥99% purity athwart 99% pure 2F-DCK legions, substantiated by disinterested inquisition to obviate contaminants imperiling exactitude. This lodestar sustains the best price 2F-DCK lab grade as an exemplar of fidelity in your probative architectures.

How Is Purity Tested for 2F-DCK?

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