Elevate your neuropharmacological research with F-Phenibut HCL, a fluorinated analog of phenibut in hydrochloride form, renowned for its role in studying GABAergic modulation and anxiolytic mechanisms. Our 99% pure F-Phenibut HCL guarantees exceptional purity for consistent, reproducible results in laboratory settings. Ideal for investigating GABAB receptor agonism and neurotransmitter dynamics, this research chemical is rigorously tested to meet the highest scientific standards.
Physical and Chemical Properties:
- Appearance: White to off-white crystalline powder
- Molecular Formula: C10H12FNO2 · HCl
- Molecular Weight: 233.67 g/mol
- CAS Number: Not assigned (research analog)
- Solubility: Highly soluble in water; soluble in ethanol, DMSO
- Melting Point: ~190-195°C (HCl salt)
- Purity Level: ≥99% (HPLC verified)
- Storage: Store at 2-8°C, away from light and moisture
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Introduction
In the intricate domain of neuroscience, where GABAergic systems govern inhibitory neurotransmission critical to anxiety, sedation, and cognitive processes, F-Phenibut HCL emerges as a potent fluorinated analog of phenibut, optimized as a hydrochloride salt for enhanced solubility and stability. With a fluorine substitution enhancing blood-brain barrier permeability and GABAB receptor affinity (Ki ~100 nM), this compound offers a refined lens into anxiolytic and sedative mechanisms. Our 99% pure F-Phenibut HCL is synthesized with meticulous precision, delivering a reagent free of impurities for seamless experimental reproducibility. Whether probing receptor kinetics in neuronal cultures or modeling stress responses in behavioral paradigms, order F-Phenibut HCL for research provides a trusted tool for global laboratories. With its improved pharmacokinetic profile, F-Phenibut HCL for research invites exploration of GABAergic modulation. Leverage our rapid, discreet global shipping, and let buy F-Phenibut HCL powder online propel your research into the forefront of neurochemical discovery, poised for recognition in journals like Neuropharmacology or Journal of Psychopharmacology.
Key Features & Benefits
Our F-Phenibut HCL is crafted to meet the rigorous demands of modern research, blending scientific excellence with practical utility:
- Exceptional 99%+ Purity: Each batch undergoes stringent testing to eliminate impurities, ensuring reliable data for studies published in high-impact journals like Neuropsychopharmacology.
- Versatile Research Applications: Ideal for order F-Phenibut HCL for research in GABAB receptor agonism, anxiolytic effects, and neurotransmitter dynamics, supporting investigations into anxiety and sedation models.
- Discreet Global Shipping: Vacuum-sealed in plain, unmarked packaging with no chemical identifiers, your purchase F-Phenibut HCL for lab use arrives confidentially, blending with standard mail.
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Product Specifications
Our 99% pure F-Phenibut HCL is characterized by precise specifications to support your research needs:
| Property | Specification |
|---|---|
| Molecular Formula | C10H12FNO2 · HCl |
| Molecular Weight | 233.67 g/mol |
| CAS Number | Not assigned (research analog) |
| Synonyms | 4-Fluorophenibut HCL, β-(4-Fluorophenyl)-GABA hydrochloride |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Solubility | Water: Highly soluble; Ethanol: Soluble; DMSO: Soluble |
| Melting Point | ~190-195°C (HCl salt) |
| Boiling Point | Decomposes above 250°C |
| Density | ~1.2 g/cm³ |
| Storage Conditions | 2-8°C, dry, away from light |
These properties ensure best price F-Phenibut HCL research chemical is a stable, versatile compound for laboratory protocols.
Applications & Usage
F-Phenibut HCL is a key asset in neuropharmacological research, aligned with standards from organizations like the Society for Neuroscience. As a GABAB receptor agonist, it is used in behavioral assays, such as the open-field test, to study anxiolytic effects, demonstrating potency comparable to baclofen with enhanced bioavailability due to fluorination. Researchers employ order F-Phenibut HCL for research in radioligand binding studies to assess GABAB receptor affinity, providing insights into inhibitory neurotransmission.
In electrophysiological studies, F-Phenibut HCL supports investigations into synaptic inhibition in cortical or hippocampal slices, aiding research into anxiety disorders and sedation mechanisms. Its high water solubility as a hydrochloride salt facilitates precise dosing in cell culture or in vivo models, adhering to GLP-compliant protocols for GABAergic drug discovery. For optimal use, dissolve in saline for intraperitoneal administration or water for oral gavage, calibrating doses via dose-response studies to establish threshold effects. Purchase F-Phenibut HCL for lab use to advance studies in GABA neuroscience and anxiolytic development.
Purity & Testing
Purity is the cornerstone of reliable research, and our 99% pure F-Phenibut HCL delivers through rigorous quality assurance. High-Performance Liquid Chromatography (HPLC) quantifies purity with detection limits below 0.05% for impurities. Nuclear Magnetic Resonance (NMR) spectroscopy confirms the molecular structure, with characteristic fluoro-aromatic and amino acid signals ensuring fidelity. Mass Spectrometry (MS) verifies the molecular ion at m/z 198 [M+H]+ for the base, with the hydrochloride adduct at 234, adhering to USP and EP analytical standards.
These methods ensure best price F-Phenibut HCL research chemical maintains ≥99% purity, reducing variability in receptor binding and behavioral assays. Enhanced data integrity supports high-impact publications in journals like Journal of Psychopharmacology. Trust our F-Phenibut HCL for precision and reproducibility.
Safety & Handling Guidelines
F-Phenibut HCL is intended strictly for research use only, not for human, veterinary, or medical applications. Researchers must be 18+ and comply with institutional safety protocols. Handle in a fume hood with nitrile gloves, safety goggles, and protective clothing to avoid skin or eye contact. Rinse exposed areas with water for 15 minutes if contact occurs.
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Legal & Safety Disclaimer
F-Phenibut HCL is supplied solely for laboratory research, not for human, veterinary, or medical use. Buyers must be 18+ and comply with local, national, and international regulations, such as EU REACH or U.S. DEA guidelines. We are not liable for misuse, and purchasers assume full responsibility for legal compliance. Consult regulatory authorities to confirm permissible use.
FAQ
What is F-Phenibut HCL used for in research?
Order F-Phenibut HCL for research to study GABAB receptor agonism, anxiolytic effects, and GABAergic modulation. It’s used in models of anxiety and sedation, as reported in Journal of Psychopharmacology and Neuropharmacology.
Is F-Phenibut HCL legal?
Legality varies by region. F-Phenibut HCL research chemical is often legal for research under controlled substances laws, provided it’s not used outside lab settings. Verify local regulations before you buy F-Phenibut HCL powder online.
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What is the purity level?
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How is purity tested?
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