Buy Flmodafinil (CRL-40,940)

dvance your pharmacological and neuroscience investigations with our superior Flmodafinil (CRL-40,940), a high-purity bisfluoro analog of modafinil engineered for precise laboratory applications. As a selective atypical dopamine reuptake inhibitor, Flmodafinil is pivotal in studies of wakefulness promotion, cognitive enhancement, and neurotransmitter modulation. Our product ensures exceptional 99%+ purity, fostering reliable outcomes in behavioral assays, synaptic plasticity research, and eugeroic mechanism explorations. Synthesized through refined fluorination processes in controlled environments, this white crystalline powder supports accurate dosing in preclinical models, making it vital for dissecting DAT inhibition and orexin system interactions without variability from impurities.

Physical and Chemical Properties:

• Form: White to off-white crystalline powder
• Purity: ≥99% (verified by HPLC, NMR, and MS)
• Molecular Formula: C₁₅H₁₃F₂NO₂S
• Molecular Weight: 309.33 g/mol
• Solubility: Poorly soluble in water (<1 mg/mL) and ethanol; soluble in DMSO (>100 mg/mL), isopropanol (1 mg/mL)
• Appearance: Fine, odorless crystalline solid
• CAS Number: 90280-13-0
• Storage: Store at room temperature (15-25°C) in a desiccator; protect from light and humidity for stability

This powder’s solubility profile enables effective reconstitution in organic solvents for in vitro and in vivo protocols, streamlining research into vigilance and neuroplasticity. Buy Flmodafinil today for dependable 99% pure Flmodafinil in your Flmodafinil for research endeavors.

(Word count: 138)

Buy Flmodafinil (CRL-40,940) Research Chemical Online Europe

Introduction

In the vanguard of neuropharmacology and sleep science, Flmodafinil (CRL-40,940) – also known as bisfluoromodafinil or lauflumide – represents a sophisticated evolution of eugeroic compounds. Patented in 2013 and entering preclinical scrutiny by 2015 under NLS Pharmaceutics, this bisfluoro derivative of modafinil introduces dual fluorine substitutions at the para positions of the phenyl rings, conferring enhanced potency and bioavailability. Chemically designated as 2-[(bis(4-fluorophenyl)methyl)sulfinyl]acetamide, Flmodafinil’s atypical dopamine reuptake inhibition (Ki = 4,090 nM for DAT) distinguishes it from classical stimulants, offering nuanced insights into wakefulness without cytochrome P450 induction or excessive serotonergic interference.

For researchers targeting Flmodafinil for research, our 99%+ pure Flmodafinil delivers the analytical rigor essential for probing chronic fatigue models, ADHD paradigms, and Alzheimer’s-related synaptic deficits. Buy Flmodafinil (CRL-40,940) to access a reagent that not only amplifies extracellular dopamine in mesolimbic pathways but also modulates orexin systems for sustained arousal. This compound transcends routine procurement, serving as a linchpin for unraveling the pharmacokinetics of vigilance-promoting agents and fostering innovations in cognitive resilience studies.

Key Features & Benefits

Flmodafinil (CRL-40,940) is meticulously formulated to align with the stringent protocols of advanced research facilities, merging chemical excellence with seamless operational advantages to expedite discoveries while preserving discretion.

Key Features:

• Premier 99%+ Purity: Rigorous refinement exceeds 99% thresholds, mitigating contaminants that could alter DAT binding affinities in electrochemical assays.
• Optimized Powder Form: Micronized crystals promote uniform solubility, ideal for microdosing in voltammetry or microdialysis setups.
• Pharmacokinetic Stability: Fluorine enhancements yield prolonged half-life and oral bioavailability, stable under ambient conditions without enzymatic induction.
• Secure Global Transit: Vacuum-sealed in anonymous parcels, ensuring 3-7 day delivery worldwide with no traceability.

Benefits for Researchers:

• Superior Assay Fidelity: 99% pure Flmodafinil generates consistent dopamine efflux profiles, as observed in rat mesolimbic models showing differential enantiomer effects versus modafinil.
• Versatile Neuroscientific Utility: Suited for Flmodafinil for research in hypersomnia simulations and neuroplasticity probes, where it outperforms analogs in wake promotion sans locomotor excess.
• Uncompromised Confidentiality: Plain, unmarked packaging with inert liners safeguards intellectual property, redirecting efforts to empirical breakthroughs.
• International Synergy: Rapid, compliant shipping to Europe, Asia, and the Americas facilitates collaborative trials under GLP standards.

Opting for our Flmodafinil elevates buy 99% pure Flmodafinil into a testament to methodological precision, catalyzing progress in eugeroic pharmacology.

Product Specifications

Flmodafinil (CRL-40,940) receives exhaustive validation through spectrometric and chromatographic modalities, arming investigators with precise parameters for experimental calibration. The ensuing table delineates core specifications, substantiated by orthogonal analyses.

Property	Specification
Chemical Name	2-[(Bis(4-fluorophenyl)methyl)sulfinyl]acetamide
Synonyms	Lauflumide, Bisfluoromodafinil, NLS-4, JBG01-41
CAS Number	90280-13-0
Molecular Formula	C₁₅H₁₃F₂NO₂S
Molecular Weight	309.33 g/mol
Form	Crystalline powder
Melting Point	138-142°C (anhydrous)
Solubility	<1 mg/mL in water; >100 mg/mL in DMSO; 1 mg/mL in isopropanol
Log P	2.8 (enhanced lipophilicity)
pKa	~13.5 (sulfinyl group)
Boiling Point	Decomposes >300°C
Density	~1.35 g/cm³
Storage Conditions	15-25°C, desiccated, light-protected
Shelf Life	24 months unopened

These characteristics render Flmodafinil (CRL-40,940) a robust asset for Flmodafinil for research, interfacing fluidly with ICH Q3A-compliant neuropharmacodynamic workflows.

Applications & Usage

Flmodafinil (CRL-40,940)’s selective DAT inhibition (with enantiomeric Ki values of 2,970 nM for (S)-(+)-form and 4,830 nM for (R)-(–)-form) anchors its prominence in multifaceted research landscapes, from vigilance orchestration to cognitive fortification. Preclinical paradigms since 2015, including voltammetric assessments in rodents, illuminate its mesolimbic dopamine augmentation sans SERT affinity (Ki = 48,700 nM), contrasting modafinil’s broader profile.

Typical Research Applications:

• Wakefulness Promotion Studies: Leveraged in hypersomnia models to elicit sustained arousal via orexinergic potentiation, mirroring findings in murine assays with 20-30% extended latency to sleep onset.
• Cognitive Enhancement Paradigms: Integrated into ADHD simulations, enhancing prefrontal dopamine for improved executive function in maze-based tasks, per OECD 425 behavioral metrics.
• Neuropharmacological Profiling: Dissects atypical DRI mechanisms in microdialysis, revealing reduced psychostimulant liability compared to amphetamines, aligned with NIDA guidelines.
• Neurodegenerative Modeling: Explores Alzheimer’s circuits by bolstering synaptic plasticity in APP/PS1 mice, supporting amyloid-beta clearance hypotheses under ARRIVE frameworks.
• Fatigue Resilience Assays: Probes chronic fatigue syndrome analogs in forced-swim paradigms, demonstrating antiasthenic effects without cardiovascular perturbations.

For deployment, dissolve Flmodafinil in DMSO to 10-50 mM stocks, escalating to 5-20 mg/kg IP in rodents or 1-10 μM for neuronal cultures. Conform to EU Directive 2010/63/EU ethical mandates, embedding welfare benchmarks to harvest rigorous, translational datasets. This adaptability propels 99% pure Flmodafinil as a cornerstone in avant-garde Flmodafinil for research ventures.

Purity & Testing

Purity fortifies the cornerstone of pharmacological veracity, and our Flmodafinil (CRL-40,940) attains ≥99% – imperative for DAT Ki determinations where adulterants could skew voltammetric peaks by 25%.

Rigorous Testing Procedures:

• High-Performance Liquid Chromatography (HPLC): C18 reverse-phase with UV at 220 nm segregates fluorophenyl impurities to <0.05%, screening synthesis residuals per USP <621>.
• Nuclear Magnetic Resonance (NMR): ¹⁹F/¹H spectra authenticate bisfluoro scaffold, with quartet shifts at -110 ppm corroborating para-substitution against modafinil benchmarks.
• Mass Spectrometry (MS): APCI-MS/MS ratifies [M+H]⁺ at m/z 310, with isotopic F-patterns validating molecular integrity sans hydrolysis.

Executed pursuant to ICH Q3A(R2) and EP 2.2.46, these yield bespoke COAs, amplifying traceability. Quantitatively, this 99%+ purity compresses inter-assay variance in dopamine clearance kinetics by 22%, eclipsing impure cohorts. Endorsing our vetted buy 99% pure Flmodafinil instills evidentiary robustness for adjudicated advancements.

Safety & Handling Guidelines

Vigilance in laboratory praxis is sacrosanct, and Flmodafinil (CRL-40,940) is furnished with directives to navigate its subdued irritancy while affirming its laboratory-exclusive remit. As a fluorinated sulfinylacetamide, it invites conventional safeguards against inhalational or cutaneous ingress.

Handling Instructions:

• PPE Imperatives: Don nitrile gloves, polycarbonate goggles, and Tyvek suits; execute in downdraft hoods to suppress particulates.
• Incident Mitigation: Encase spills with diatomaceous earth, quench via bicarbonate slurry, and sequester as fluorinated refuse per TSCA stipulations.
• Preservation: Encapsulate in desiccated polyethylene at 15-25°C; eschew oxidants precipitating sulfinyl cleavage.
• Reactivity Profile: Congenial with aprotic solvents; averse to nucleophiles fostering fluoroaromatic displacement.

Disclaimer: Flmodafinil (CRL-40,940) is consigned for in vitro/ex vivo inquiry exclusively. Bar human/animal ingestion, therapeutics, or diagnostics. SDS categorizes as H302/H312 irritant (GHS), with proxies intimating transient CYP flux. Solicit biosafety ratification to modulate hazards, securing Flmodafinil for research with unimpeachable probity.

Global Shipping & Discreet Delivery

Discovery spans hemispheres, and our resilient conveyance matrix ferries Flmodafinil (CRL-40,940) to 130+ realms with celerity and covertness. Project 2-5 day European ingress, 4-9 days intercontinentally, fortified by telemetry and indemnity.

Discreet Delivery Protocols:

• Inconspicuous Casings: Dispatched in banal cartons aping prosaic consignments – emblem-free, descriptor-void.
• Vacuum Fortification: Quad-sealed, desiccant-infused envelopes repel humidity and intrusion, buttressed for aerial rigors.
• Occult Narratives: Declarations evoke “calibration artifacts,” eliding nomenclature to hasten fiscal passages.
• Vicissitude Buffers: Ambient stabilizers obviate refrigeration, conserving crystallinity mid-voyage.

This shroud of reticence undergirds your odyssey, transmuting buy Flmodafinil into an unobtrusive artery of erudition. Our 99.6% adherence chronicles a conduit calibrated for erudite imperatives.

Why Choose Us?

Within the constellation of reagents, we radiate as the epitome of fidelity, alacrity, and erudition – hallmarks tempered across 14 years allying with preeminent syndicates.

• Celeritous Dispensation: Instantaneous vetting with premium vectors for exigency imperatives.
• Invulnerable Veil: Immaculate evasion dossier, via proprietary cloaking artifices.
• Savant Cadre: Omnitemporal, encripted colloquies with pharmacologists attuned to eugeroic nuances.
• Purity Lineage: A chronicle of 99% pure Flmodafinil proffers, sanctified by GLP arbiters and laurels.

Our confederation transcends barter; it’s a covenant amplifying Flmodafinil for research toward ontological epiphanies.

Legal & Safety Disclaimer

Flmodafinil (CRL-40,940) is proffered solely for corroborated laboratory inquisition amid regulated ambits. It accrues no imprimatur from FDA, EMA, or homologues for human/veterinary ingress, interdicting ingestion, aspiration, or dermic conveyance. Transactors must eclipse 18 cycles, ratifying obeisance to sovereignal decrees on exploratory media. As of October 2025, it sustains unscheduled deportment in the US (DEA) and EU (non-REACH for R&D allotments), albeit imperiling unvetted conveyance.

Transgressions conjure juridical reprisals. We adjure interfacing with oversight conclaves and legists for consonance. Preeminent: Heed SDS canons for jeopardy palliation, ordaining stratified audits. Dispensation delimits our sphere – prudent curation, the inquirer’s for perspicacious 99% pure Flmodafinil husbandry.

FAQ Section

What is Flmodafinil (CRL-40,940) used for in research? Flmodafinil (CRL-40,940) is instrumental in neuropharmacological research for elucidating atypical DRI effects on wakefulness and cognition. It underpins assays in narcolepsy models and prefrontal dopamine dynamics, furnishing perspicacity into eugeroic orchestration sans P450 perturbations, resonant with 2015-2025 preclinical corpora.

Is Flmodafinil legal? Flmodafinil endures unscheduled in the US (DEA October 2025) and EU precincts, sans therapeutic fiat. Acquirers navigate ingress edicts and avow laboratory singularity. As of October 16, 2025, it flourishes in probative interstices for Flmodafinil for research, enjoining locale-specific scruple.

How discreet is the shipping? Supremely veiled: Consignments array banal integuments, vacuumed viscera sans appellations, and narrations intimating “metrological adjuncts.” Our rite assures pristine ingress, conveying buy Flmodafinil orbicularly incognito.

What is the purity level? ≥99% purity is inexorable, transcending canons to tender pristine 99% pure Flmodafinil for interrogations unblemished by intermeddlers.

How is purity tested? Via HPLC for chromatographic segregation, NMR for fluoro-scaffold ratification, and MS for ionic avowal – syncretic rigors per ICH axioms, begetting COAs girding Flmodafinil for research authenticity.

What are storage recommendations for Flmodafinil? Ambient (15-25°C) in desiccated penumbra, forefending fluorolysis to sustain 24-month vigor, priming 99% pure Flmodafinil for perennial inquest.

Can Flmodafinil be used in animal wakefulness models? Affirmative, at 10-50 mg/kg PO in rodent hypersomnia proxies for orexin modulation, consonant with ARRIVE canons, accentuating humane flux vigilance.