Advance your investigations in synthetic chemistry and neuropharmacology with our high-quality 4F-MAR (4-Fluoro-4-methylaminorex), a fluorinated analog of 4-methylaminorex designed for precise studies of structure-activity relationships in stimulant-like compounds. This oxazoline derivative enables detailed exploration of monoamine transporter dynamics and synthetic pathways, offering consistency critical for reproducible results. Our 4F-MAR for research achieves 99%+ purity through advanced refinement, free from impurities that could interfere with analytical techniques like mass spectrometry or binding assays, making it a vital asset for laboratories dedicated to innovative pharmacological modeling.

Physical and Chemical Properties:

• Appearance: White to off-white crystalline powder, uniform and non-hygroscopic
• Molecular Formula: C10H11FN2O
• Molecular Weight: 194.21 g/mol
• Solubility: Highly soluble in DMSO (>100 mg/mL) and methanol; sparingly soluble in water (≈5 mg/mL at neutral pH)
• Melting Point: 160-164°C (as diastereomer mixture)
• Purity Level: 99.5%+ confirmed by HPLC and LC-HRMS
• CAS Number: 1364933-64-1
• Storage: In a cool, dark place under inert atmosphere at 2-8°C to maintain stability

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Buy 4F-MAR Research Chemical Online Europe

Introduction

In the rapidly advancing field of designer drug analogs and psychopharmacology, 4F-MAR (4-Fluoro-4-methylaminorex) represents a sophisticated tool for researchers probing the nuances of halogenated stimulants. This para-fluoro substituted derivative of 4-methylaminorex, featuring a 2-aminooxazoline core with a fluorophenyl moiety, has emerged as a key subject in studies of neurotransmitter modulation since its initial detection in 2018. Its structural elegance allows for targeted investigations into fluorine’s impact on lipophilicity, receptor binding, and metabolic profiles, bridging gaps in understanding synthetic cathinone alternatives.

As a premier provider of analytical research chemicals, we deliver 99% pure 4F-MAR that meets the exacting requirements of global laboratories, ensuring your work stands up to scrutiny in high-impact publications. Struggling with unreliable vendors or protracted delivery times? When you order 4F-MAR powder online, our streamlined process guarantees premium material arrives promptly and privately, empowering your explorations in amine transporter kinetics or synthetic methodology. Whether dissecting stereoisomeric effects via chiral chromatography or modeling uptake inhibition, our purchase 4F-MAR research chemical selection accelerates progress. Embrace the forefront of chemical innovation—4F-MAR is your ally in unveiling tomorrow’s discoveries.

Key Features & Benefits

Revolutionize your experimental paradigms with the refined characteristics of our lab-grade 4F-MAR, engineered to integrate seamlessly into rigorous scientific workflows. This compound transcends mere utility, serving as a benchmark for precision in pharmacological research. Uncover the compelling reasons why experts turn to us for buy 4F-MAR for research:

• Exceptional 99%+ Purity: Rigorously purified to surpass analytical thresholds, our 4F-MAR minimizes artifacts in sensitive assays, such as HRMS fragmentation patterns or enantioselective separations, delivering data you can trust.
• Diverse Research Applications: Tailored for inquiries into halogen effects on monoamine systems, synthetic route optimization, and forensic profiling—our 4F-MAR for research supports multifaceted studies with unwavering reliability.
• Stealth Discreet Packaging: Shipments are encased in vacuum-sealed, tamper-resistant liners within nondescript exteriors, featuring blank labels and no traceability to contents for absolute discretion.
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Product Specifications

Our commitment to analytical excellence is embodied in the precise specifications of 4F-MAR, aligned with international benchmarks such as those from the International Council for Harmonisation (ICH). These details facilitate informed integration into your protocols, from synthesis to characterization. Explore the technical profile:

Property	Specification
Molecular Structure	2-Amino-5-(4-fluorophenyl)-4-methyl-4,5-dihydrooxazole (racemic mixture)
Purity	≥99.5% (HPLC, diastereomer blend)
Particle Size	20-80 μm (fine for rapid solubilization)
Density	1.18 g/cm³
¹H NMR Key Signals	δ 1.25 (d, 3H, CH₃), 4.85-5.10 (m, 2H, oxazoline CH), 7.05-7.25 (m, 4H, Ar-H)
Stability	Stable under refrigeration; avoid prolonged light exposure
Packaging Options	250mg, 500mg, 1g in inert-sealed glass vials

These attributes make order 4F-MAR powder online a strategic choice for researchers utilizing NMR elucidation or LC-HRMS verification. In comparisons for purchase 4F-MAR research chemical, our specs highlight superior consistency and compatibility.

Applications & Usage

4F-MAR excels as a probe in the study of substituted aminorexes, particularly for elucidating the role of para-halogenation in stimulant pharmacophores. In forensic science, it’s instrumental in identifying novel psychoactive substances (NPS) through HRMS libraries, as per European Monitoring Centre for Drugs and Drug Addiction (EMCDDA) protocols. Pharmacologists deploy 4F-MAR for research to assess DAT/NET/SERT affinities via radioligand displacement, informing structure-toxicity correlations in line with publications from Forensic Science International.

Synthetic chemists value it for exploring regioselective fluorination routes, while toxicologists map its biotransformation using hepatocyte models. For practical implementation, sonicate in DMSO to 20 mM stocks, then dilute into aqueous buffers; employ chiral HPLC for diastereomer resolution if stereospecificity is required. Our formulation ensures optimal performance across these domains, fostering advancements in chemical forensics and beyond. Strictly laboratory-bound, always align with institutional biosafety levels and SDS directives.

Purity & Testing

Purity underpins the validity of every research endeavor, and our 99% pure 4F-MAR is fortified by an exhaustive analytical cascade to affirm its superlative quality. Liquid chromatography-high-resolution mass spectrometry (LC-HRMS) delineates isotopic patterns and fluorine couplings (¹J_C-F ≈245 Hz), complemented by high-performance liquid chromatography (HPLC) for diastereomeric quantification at 220 nm. Nuclear magnetic resonance (NMR) spectroscopy validates structural fidelity, detecting impurities below 0.1% via integration of diagnostic peaks.

Adhering to ICH Q3A(B) guidelines, this regimen curtails variability in downstream applications, such as accurate mass confirmation or purity-adjusted dosing in microdialysis studies. Accompanying each buy 4F-MAR for research order is a comprehensive certificate of analysis (CoA), replete with chromatograms and spectra, to underpin your documentation needs. In an landscape demanding irrefutable integrity, our multi-modal testing for 99% pure 4F-MAR elevates confidence in your findings.

Safety & Handling Guidelines

Laboratory safety is paramount when engaging with synthetic amines like 4F-MAR, and we furnish detailed measures to mitigate associated risks. As a fine powder, it warrants handling in a Class II biosafety cabinet with laminar flow, donning appropriate PPE: powder-rated respirators (N95+), chemical-resistant gloves, and full-face shields to avert inhalation or percutaneous uptake.

In event of exposure, flush affected areas copiously and administer activated charcoal if ingestion is suspected, followed by professional evaluation. Maintain under desiccated, inert conditions to forestall oxidative decay, and dispose via approved incineration conforming to EPA or equivalent standards. Designated solely for research—no endorsement for human/animal administration, diagnostics, or extraneous uses. Eligible purchasers (18+) bear responsibility for jurisdictional adherence; non-compliance nullifies guarantees and incurs sole liability.

Global Shipping & Discreet Delivery

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Legal & Safety Disclaimer

4F-MAR is proffered exclusively for authenticated laboratory research and is impermissible for human or veterinary ingestion, therapeutic experimentation, or consumptive pursuits. Acquirers must exceed 18 years, affirming consonance with all germane local, federal, and transnational edicts on analytical reagents. We disavow liability for aberrant deployment, with buyers indemnifying against derivative assertions. Solicit juridical counsel for locale-tailored interpretations, and peruse the adjunct SDS for exhaustive peril and abatement intelligence.

FAQ

What is 4F-MAR Used for in Research?

4F-MAR (4-Fluoro-4-methylaminorex) is pivotal in 4F-MAR for research, facilitating dissections of fluorination’s influence on aminorex scaffolds, including transporter selectivity and metabolic trajectories. It underpins forensic NPS identification and synthetic analog profiling, consonant with EMCDDA methodologies, sans non-laboratory inferences.

Is 4F-MAR Legal?

As an analytical reagent, 99% pure 4F-MAR is viable for scholarly procurement in select domains when restricted to credentialed lab environs. Regulatory variance obtains; we proffer export facilitation to underpin lawful purchase 4F-MAR research chemical engagements—diligence on statutes is incumbent.

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What Is the Purity Level of Your 4F-MAR?

We avow ≥99% purity across 99% pure 4F-MAR cohorts, corroborated by impartial scrutiny to obviate adulterants imperiling precision. This benchmark sustains the best price 4F-MAR lab grade as a paragon of dependability in your investigative frameworks.

How Is Purity Tested for 4F-MAR?

Scrutiny invokes LC-HRMS for elemental mapping and fluorine metrics, HPLC for quantitative delineation, and NMR for configurational attestation—paradigms echoing ICH stipulations. These engender the CoA with your buy 4F-MAR for research, ratifying probity for dossiers and oversight.