Propel your cognitive neuroscience research with our elite Fasoracetam, a meticulously purified racetam derivative crafted for demanding laboratory applications. As a potent modulator of metabotropic glutamate receptors (mGluRs), Fasoracetam is a key player in investigations into synaptic plasticity, memory consolidation, and neurotransmitter regulation. Our formulation achieves extraordinary 99%+ purity, delivering unwavering consistency for in vitro neuronal assays, behavioral pharmacology, and molecular signaling studies. Produced via advanced synthetic routes in GMP-compliant environments, this fine white powder supports precise microgram-scale dosing, making it indispensable for exploring GABAergic and glutamatergic pathways without formulation artifacts. Buy Fasoracetam
Physical and Chemical Properties:
- Form: White to off-white crystalline powder
- Purity: ≥99% (validated by HPLC, NMR, and MS)
- Molecular Formula: C₁₀H₁₆N₂O₂
- Molecular Weight: 196.25 g/mol
- Solubility: Freely soluble in water (>10 mg/mL), DMSO (>50 mg/mL), and ethanol (5-10 mg/mL); sparingly soluble in non-polar solvents
- Appearance: Fine, odorless crystalline solid
- CAS Number: 110958-19-5
- Storage: Store at room temperature (15-25°C) in a desiccator; protect from light and humidity to maintain stability
This powder’s excellent water solubility facilitates easy dissolution for aqueous media, streamlining protocols in cell culture and animal model experiments. Buy Fasoracetam today to secure 99% pure Fasoracetam for transformative Fasoracetam for research insights.
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Buy Fasoracetam Research Chemical Online Europe
Introduction
Within the intricate domain of nootropic and neuropharmacology research, Fasoracetam shines as an innovative racetam scaffold that unlocks profound questions about brain plasticity and cognitive resilience. Developed in the 1990s by Nippon Shinyaku as a potential therapeutic for vascular dementia, Fasoracetam – systematically (5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one – distinguishes itself through its selective interactions with group II/III metabotropic glutamate receptors (mGluRs) and GABA-B receptors. Though clinical trials revealed limited efficacy for certain indications, its mechanistic elegance has fueled a renaissance in preclinical studies, probing everything from synaptic transmission to anxiolytic modulation.
Researchers seeking Fasoracetam for research will find our 99%+ pure Fasoracetam an exemplary choice, free from impurities that could obscure subtle receptor dynamics. Buy Fasoracetam to integrate a compound that not only upregulates glutamate transporter expression but also enhances cholinergic signaling, fostering reproducible data in models of learning deficits and mood dysregulation. Far beyond a mere reagent, this high-fidelity powder is a gateway to elucidating the glutamate-GABA interplay, driving discoveries that could reshape paradigms in cognitive enhancement and neurodevelopmental research.
Key Features & Benefits
Fasoracetam is precision-engineered for the uncompromising standards of elite research labs, blending superior chemical integrity with logistical excellence to accelerate your investigative momentum while upholding discretion.
Key Features:
- Unrivaled 99%+ Purity: Batches are exhaustively refined to exceed 99% purity, curtailing contaminants that might interfere with receptor binding kinetics.
- Versatile Powder Morphology: Ultra-fine crystals ensure rapid, homogeneous dissolution, suiting a spectrum of assay formats from patch-clamp electrophysiology to high-content screening.
- Robust Thermal Stability: Maintains structural fidelity across standard lab conditions, with polymorphic controls to prevent hydrate formation variability.
- Confidential Worldwide Logistics: Dispatched in vacuum-sealed, nondescript parcels with zero identifiers, achieving 3-7 day global transit.
Benefits for Researchers:
- Precision in Mechanism Studies: 99% pure Fasoracetam yields tight dose-response curves in mGluR modulation assays, as seen in rodent models exhibiting enhanced long-term potentiation without off-target effects.
- Expanded Research Horizons: Tailored for Fasoracetam for research in synaptic plasticity and anxiolysis, where it augments GABA-B desensitization reversal in chronic stress paradigms.
- Seamless Privacy Integration: Stealth packaging – plain exteriors and unmarked manifests – safeguards proprietary protocols, letting science take precedence.
- Borderless Efficiency: Tracked, insured delivery across Europe, North America, and Asia streamlines multinational consortia, minimizing downtime.
Embracing our Fasoracetam transforms buy 99% pure Fasoracetam into a cornerstone of methodological rigor, propelling your lab toward peerless reproducibility and innovation.
Product Specifications
Fasoracetam is subjected to comprehensive physicochemical profiling via cutting-edge analytics, equipping researchers with actionable metrics for experimental design. The table below encapsulates essential specifications, corroborated by crystallographic and spectrometric data.
| Property | Specification |
|---|---|
| Chemical Name | (5R)-5-(Piperidine-1-carbonyl)pyrrolidin-2-one |
| Synonyms | NS-105, LAM-105, NFC-1 |
| CAS Number | 110958-19-5 |
| Molecular Formula | C₁₀H₁₆N₂O₂ |
| Molecular Weight | 196.25 g/mol |
| Form | Crystalline powder |
| Melting Point | 132-136°C (anhydrous form) |
| Solubility | >10 mg/mL in water; >50 mg/mL in DMSO; 5-10 mg/mL in ethanol |
| Log P | 0.12 (indicating hydrophilic nature) |
| pKa | ~3.5 (pyrrolidone carbonyl) |
| Boiling Point | Decomposes >250°C |
| Density | ~1.25 g/cm³ |
| Storage Conditions | 15-25°C, desiccated, light-protected |
| Shelf Life | 24 months unopened |
These attributes position Fasoracetam as a premier candidate for Fasoracetam for research, harmonizing with ICH-compliant workflows in neurochemical evaluations.
Applications & Usage
Fasoracetam’s affinity for mGluR2/3 and mGluR5 subtypes has entrenched it in a wide array of research pursuits, from dissecting glutamatergic dysregulation to modeling neurodevelopmental anomalies. Initial Phase III trials in the 1990s underscored its cholinergic augmentation in memory paradigms, while contemporary studies leverage its GABA-B upregulation for anxiety circuit mapping, as evidenced in hippocampal slice preparations showing normalized inhibitory tone.
Typical Research Applications:
- Synaptic Plasticity Investigations: Deployed to enhance LTP induction in organotypic cultures, aligning with data indicating 20-30% potentiation via mGluR-mediated endocannabinoid release.
- Cognitive Deficit Modeling: Utilized in scopolamine-induced amnesia assays, where it restores spatial navigation in Morris water maze tasks per standardized behavioral neuroscience protocols.
- Anxiolytic Pathway Research: Probes prefrontal-amygdala connectivity in elevated plus-maze models, supporting GABA-B receptor resensitization consistent with OECD 425 guidelines.
- Neurodevelopmental Studies: Explores mGluR polymorphisms in ADHD-like phenotypes, contributing to genetic subtype analyses in zebrafish or murine knock-ins under ARRIVE-compliant designs.
- Mood Regulation Assays: Examines serotonin-glutamate crosstalk in forced swim tests, revealing antidepressant-like reductions in immobility without monoamine perturbations.
In practice, reconstitute Fasoracetam in sterile water or PBS to 1-10 mM stocks, titrating to 0.1-5 mg/kg for IP administration in rodents or 10-50 μM for neuronal co-cultures. Adhere to ethical frameworks like EU Directive 2010/63/EU, incorporating humane endpoints to generate defensible, impactful datasets. This breadth cements 99% pure Fasoracetam as a linchpin in pioneering Fasoracetam for research endeavors.
Purity & Testing
Purity underpins the veracity of neuroscientific inquiry, and our Fasoracetam attains ≥99% purity – a benchmark indispensable for discerning mGluR subtype selectivity, where impurities could inflate IC50 variances by orders of magnitude.
Rigorous Testing Procedures:
- High-Performance Liquid Chromatography (HPLC): Reverse-phase separation with UV detection at 210 nm resolves impurities to <0.1%, vital for quantifying residual solvents or diastereomeric byproducts.
- Nuclear Magnetic Resonance (NMR): ¹H/¹³C spectra delineate the pyrrolidone-piperidine scaffold, with diagnostic shifts at 4.5 ppm (chiral methine) affirming stereochemical purity against reference libraries.
- Mass Spectrometry (MS): ESI-MS/MS confirms [M+H]⁺ at m/z 197.129, with fragmentation patterns validating amide linkages and excluding hydrolysis artifacts.
These assays, executed per USP <621> and ICH Q3A guidelines, accompany each shipment with detailed COAs, fortifying experimental traceability. Empirically, this 99%+ purity slashes inter-batch deviations in receptor autoradiography by 18%, vis-à-vis lesser sources. Selecting our certified buy 99% pure Fasoracetam arms your pursuits with the analytical fortitude for irrefutable findings.
Safety & Handling Guidelines
Laboratory stewardship is foundational, and Fasoracetam is provisioned with protocols to address its low-hazard profile while reinforcing its stringent research-only ethos. As a racetam amide, it poses minimal acute risks but necessitates routine precautions against dermal sensitization.
Handling Instructions:
- PPE Mandates: Utilize latex or nitrile gloves, safety spectacles, and lab attire; perform weigh-outs in laminar flow hoods to preclude aerosolization.
- Containment Measures: For spills, deploy absorbent pads, quench with dilute acetic acid if hydrated, and remediate as non-hazardous per EPA protocols.
- Storage Protocols: Retain in foil-wrapped vials at ambient humidity <50%; avert prolonged heat to mitigate polymorphic transitions.
- Reactivity Notes: Compatible with aqueous buffers; incompatible with strong acids that hydrolyze the lactam ring, potentially yielding pyroglutamic acid.
Disclaimer: Fasoracetam is exclusively for laboratory research and is prohibited for human or veterinary consumption, diagnostics, or therapeutics. SDS classifies it as non-irritant (GHS Category 3), though subchronic exposures in models suggest mild hepatic flux. Engage biosafety oversight to calibrate risks, ensuring Fasoracetam for research proceeds with uncompromised integrity.
Global Shipping & Discreet Delivery
Innovation defies frontiers, and our optimized dispatch infrastructure conveys Fasoracetam to 120+ nations with alacrity and anonymity. Envision 2-5 day EU fulfillment, 4-8 days internationally, augmented by GPS tracking and loss mitigation.
Discreet Delivery Protocols:
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- Vacuum Encapsulation: Triple-sealed, moisture-barrier pouches deter degradation and scrutiny, with desiccants for transit resilience.
- Veiled Declarations: Invoices denote “analytical standards,” eschewing nomenclature to expedite clearances.
- Climatic Controls: Ambient-stable padding preserves crystallinity, sans refrigeration needs.
This veil of discretion buttresses your endeavors, rendering buy Fasoracetam a fluid extension of discovery. Our 99.7% punctuality attests to a supply chain sculpted for scholarly exigencies.
Why Choose Us?
In the teeming arena of research reagents, we ascend as the paragon of dependability, expedition, and erudition – credentials burnished across 12+ years partnering with vanguard institutions.
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Our alliance elevates Fasoracetam for research beyond procurement, into symbiotic strides toward epochal neuroinsights.
Legal & Safety Disclaimer
Fasoracetam is tendered solely for authenticated laboratory scrutiny in sanctioned milieus. It garners no approbation from FDA, EMA, or equivalents for human/animal deployment and is interdicted for ingestion, inhalation, or transdermal routes. Acquirers must surpass 18 annums, attesting fealty to territorial edicts on investigational agents. As of 2025, it sustains unscheduled status in the US (DEA) and EU (non-REACH harmonized for R&D), yet imperils unendorsed dissemination.
Transgressions court penal strictures. We exhort interfacing with IRBs and jurists for conformance. Preeminent: Abide SDS edicts for peril abatement, enacting tiered evaluations. Provision is our remit – sagacious husbandry, yours for judicious 99% pure Fasoracetam curation.
FAQ Section
What is Fasoracetam used for in research? Fasoracetam is harnessed in nootropic and neuropharmacology research to interrogate mGluR-mediated synaptic plasticity and GABA-B modulation. It facilitates probes into memory encoding in LTP-deficient models and anxiolytic circuits in amygdala slices, yielding revelations on cognitive augmentation sans stimulant liabilities, consonant with 1990s Nippon Shinyaku paradigms.
Is Fasoracetam legal? Fasoracetam endures as a non-scheduled research chemical in the US (DEA 2025) and EU realms, sans therapeutic imprimatur. Purchasers must navigate import strictures and avow lab exclusivity. Per October 2025, it thrives in investigational interstices for Fasoracetam for research, mandating locale-specific diligence.
How discreet is the shipping? Impeccably veiled: Dispatches don banal casings, vacuumed cores sans descriptors, and manifests intimating “specimen kits.” Our regimen assures flawless ingress, ferrying buy Fasoracetam globally incognito.
What is the purity level? ≥99% purity is inviolable, eclipsing norms to proffer immaculate 99% pure Fasoracetam for assays unmarred by interlopers.
How is purity tested? Employing HPLC for elution profiling, NMR for scaffold authentication, and MS for ionic corroboration – synoptic rigors per ICH tenets, engendering COAs that gird Fasoracetam for research authenticity.
What are optimal storage conditions for Fasoracetam? Ambient (15-25°C) in desiccated obscurity, forestalling hydration to uphold 24-month potency, priming 99% pure Fasoracetam for enduring scrutiny.
Can Fasoracetam be integrated into cell culture studies? Affirmative, at 10-100 μM in glia-neuron co-cultures for mGluR trafficking assays, per ASTM biosafety mores, accentuating ethical flux monitoring.

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