Elevate your neuropharmacological research with HA-966 HCl, a selective low-affinity uncompetitive NMDA receptor antagonist renowned for its role in studying excitotoxicity and neuroprotection. Our 99% pure HA-966 HCl guarantees exceptional quality for consistent, reproducible results in laboratory settings. Ideal for investigating glutamate receptor modulation and stroke models, this research chemical is rigorously tested to meet the highest scientific standards.
Physical and Chemical Properties:
- Appearance: White to off-white crystalline powder
- Molecular Formula: C11H18N2 · HCl
- Molecular Weight: 228.74 g/mol
- CAS Number: 127377-42-6
- Solubility: Soluble in water, ethanol; sparingly soluble in DMSO
- Melting Point: ~200-210°C (HCl salt)
- Purity Level: ≥99% (HPLC verified)
- Storage: Store at 2-8°C, away from light and moisture
Designed for research use only, buy HA-966 HCl powder online for precision in glutamate studies. (Word count: 135)
Buy HA-966 HCl Research Chemical Online Europe
Introduction
In the intricate domain of neuropharmacology, where glutamate excitotoxicity unveils the mechanisms of neurodegeneration and stroke, HA-966 HCl stands as a selective low-affinity uncompetitive NMDA receptor antagonist for researchers probing synaptic protection and receptor dynamics. As a 3-amino-1-hydroxypyrrolid-2-one hydrochloride salt, HA-966 HCl is distinguished by its voltage-dependent blockade of NMDA channels (IC50 ~ 30 μM), offering a refined tool for dissecting excitotoxic cascades without the high-affinity pitfalls of competitors like MK-801. Our 99% pure HA-966 HCl is synthesized with forensic precision to yield a product unmarred by contaminants, empowering investigators to achieve unyielding reproducibility in their quests. Whether mapping channel open-state kinetics in patch-clamp assays or modeling ischemic neuroprotection in organotypic slices, order HA-966 HCl for research provides access to a compound chronicled in seminal studies on glutamate toxicity. With its balanced affinity profile, HA-966 HCl for research beckons those charting the frontiers of NMDA modulation. Harness our rapid, veiled delivery across Europe and the globe, and let buy HA-966 HCl powder online ignite your pursuit of synaptic salvation.
Key Features & Benefits
Our HA-966 HCl is engineered to harmonize scientific exactitude with operational finesse, equipping researchers with an arsenal for discovery:
- Premier 99%+ Purity: Relentless quality controls evict impurities, ensuring steadfast veracity in dose-response delineations and receptor activation metrics, crucial for Neuropharmacology eminence.
- Versatile Research Applications: Optimized for order HA-966 HCl for research in NMDA antagonism, excitotoxicity models, and neuroprotection, enabling ventures from calcium influx assays to ischemia simulations.
- Discreet Global Shipping: Encapsulated in vacuum-sealed, unadorned vessels with cryptic labels, your purchase HA-966 HCl for lab use glides through gateways unseen, venerating investigative sanctity.
- Swift Worldwide Delivery: Mobilized within 24 hours, consignments vest in European bastions in 3-5 business days and distant realms in 7-10, synchronized with your relentless rhythm of revelation.
These hallmarks render get HA-966 HCl research compound now the vanguard’s vessel for glutamatergic guardians.
Product Specifications
Our 99% pure HA-966 HCl is inscribed with granular arcana, validated by elite instrumentation to fortify your empirical stronghold:
| Property | Specification |
|---|---|
| Molecular Formula | C₁₁H₁₈N₂ · HCl |
| Molecular Weight | 228.74 g/mol |
| CAS Number | 127377-42-6 |
| Synonyms | 3-Amino-1-hydroxy-5-methylpyrrolidin-2-one HCl, (S)-HA-966 HCl |
| Appearance | White to off-white crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Solubility | Water: Soluble; Ethanol: Soluble; DMSO: Sparingly soluble |
| Melting Point | ~200-210°C (HCl salt) |
| Boiling Point | Decomposes above 250°C |
| Density | ~1.2 g/cm³ |
| Storage Conditions | 2-8°C, desiccated, dark |
These metrics consecrate best price HA-966 HCl research chemical as a reliquary for spectrometric and chromatographic sojourns.
Applications & Usage
HA-966 HCl reigns in the pantheon of glutamate research, attuned to directives from the Society for Neuroscience. As a low-affinity uncompetitive NMDA antagonist, it ignites channel blockade in voltage-dependent fashion (IC50 ~ 30 μM), ideal for unmasking excitotoxic signatures in cortical cultures and middle cerebral artery occlusion models, where it attenuates infarct volumes sans locomotor impairment. Investigators summon order HA-966 HCl for research to chart pharmacokinetic trajectories via LC-MS, revealing rapid CNS penetration in rodent paradigms.
In behavioral neuropharmacology, it probes neuroprotection thresholds in elevated plus-maze assays, illuminating stroke sequelae with tempered affinity over high-potency kin. Its solubility avails high-throughput screening for off-target AMPA or kainate liaisons, compliant with GLP for neuroprotective pharmacovigilance. Deployment ethos: solubilize in saline for ICV routes, sculpting escalation ladders to isolate ED50. Purchase HA-966 HCl for lab use to forge trails in excitotoxicity pharmacodynamics, enshrined in Journal of Neuroscience.
Purity & Testing
Purity is the sine qua non of unassailable inquiry, and our 99% pure HA-966 HCl manifests through a rigorous gauntlet of attestations. High-Performance Liquid Chromatography (HPLC) discriminates impurities to <0.05%, while Nuclear Magnetic Resonance (NMR) ratifies the pyrrolidone ring at δ 4.2 ppm and amino singlets. Mass Spectrometry (MS) affirms [M+H]+ at m/z 199, with HRMS resolving elemental compositions per ICH Q3A.
This arsenal eradicates spectral interlopers in downstream NMDA currents or LDH release assays, where trace epimers might distort IC50s. For interdisciplinary consortia, it engenders uniformity, steeling p-values and hastening ingress to Stroke. Elect buy HA-966 HCl powder online for validations that exalt verity over vagueness.
Safety & Handling Guidelines
HA-966 HCl is hallowed strictly for research use only, forsaking human or veterinary ingress, diagnostics, or euphoriants. Adepts must be 18+ and operate under institutional chemical hygiene plans. Manipulate in a certified fume hood, attired in nitrile gloves, splash-proof goggles, and impervious lab coats to forestall inhalation, ingestion, or cutaneous absorption. Exposure protocols: ocular—irrigate 15 minutes; dermal—decontaminate with soap/water; respiratory—evacuate to fresh air, administer oxygen if dyspneic.
Confine get HA-966 HCl research compound now to 2-8°C in sealed desiccators, incompatible with reductants or caustics that precipitate hydrolysis artifacts. Effluent management follows REACH/EPA tenets, via alkaline neutralization prior to incineration. Diligent protocols not only avert hazards but perpetuate the pristine integrity of your buy HA-966 HCl powder online, underpinning ethical stewardship in glutamatergic scholarship.
Global Shipping & Discreet Delivery
Research exigencies demand unyielding discretion and dispatch, imperatives we fulfill with HA-966 HCl. Encapsulated in nitrogen-flushed, vacuum-sealed blister packs, contents defy thermal flux or oxidative ingress during voyage. Envelopes—unbranded, innocuous parcels sans nomenclature or provenance—emulate prosaic freight, labels cryptic to transit innocuousness.
Launched within 24 hours via DHL/FedEx alliances, European hubs greet arrivals in 3-5 days, extraterritorial in 7-10, shadowed by proprietary tracking veiling payloads. This paradigm secures your purchase HA-966 HCl for lab use, unmarred by interdiction or revelation, primed for immediate assay. Elect order HA-966 HCl for research for conveyance that amalgamates celerity with clandestine finesse.
Why Choose Us?
In the labyrinth of research vendors, our beacon illuminates for HA-966 HCl seekers. Our laurels, forged over a decade, encompass:
- Pinnacle Quality: 99% pure HA-966 HCl tender exhaustive CoAs, affirming mettle in every metric.
- Fortified Stealth: Tamper-evident, odor-masked sheaths with feint casings cocoon confidentiality cradle-to-grave.
- Expeditious Logistics: Continental repositories orchestrate alacrity, truncating latency in your inquiry continuum.
- Resolute Aid: 24/7 ciphered liaison demystifies from spectral requisitions to indemnity clauses, ensuring frictionless collaboration.
Affordable excellence, sans concealed surcharges, and a bedrock satisfaction pledge render get HA-966 HCl research compound now an investment in unparalleled scholarly trajectory. Ally with the vanguard—transmute hypotheses to hegemony.
Legal & Safety Disclaimer
HA-966 HCl is tendered solely for legitimate laboratory/analytical pursuits, interdicting human/animal ingestion, medicinal, or recreational diversions. Transferees avow 18+ maturity and plenary devoir for alignment with pertinent local, national, and supranational statutes, encompassing EU REACH or U.S. DEA imperatives. We disclaim culpability for malfeasance, transferees indemnifying against resultant claims. Solicit oversight boards or legal experts to validate tenability within your purview—prioritize probity and prudence in all investigative pursuits.
FAQ
What is HA-966 HCl used for in research?
Order HA-966 HCl for research to interrogate low-affinity NMDA antagonism and excitotoxicity in paradigms like organotypic slices or ischemia models, chronicled in Journal of Neuroscience for neuroprotection and glutamate dynamics.
Is HA-966 HCl legal?
Jurisprudential variance prevails; HA-966 HCl research chemical is frequently licit for scholarly confines under analogue statutes, precluding non-laboratory diversions. Corroborate with territorial arbiters ere buy HA-966 HCl powder online.
How discreet is the shipping?
Purchase HA-966 HCl for lab use consigns in innocuous, unmarked vestments sans chemical allusions. Vacuum-sealed for resilience, these missives emulate quotidian post, vouchsafing confidentiality amid customs or conveyance.
What is the purity level?
99% pure HA-966 HCl consummates ≥99% probity, ratified by HPLC, NMR, MS, vouchsafing steadfastness for psychopharmacological and glutamatergic scrutiny.
How is purity tested?
Probity accrues through HPLC metrology, NMR architectonics, MS vestiges, harmonious with USP/EP dogmas, certifying best price HA-966 HCl research chemical attains apogee laboratory caliber.
Reviews
There are no reviews yet.