Buy Nooglutyl

Elevate your neuropharmacological research with our premium Nooglutyl, a high-purity nootropic derivative synthesized for advanced laboratory applications. As N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid, Nooglutyl is a key compound in studies exploring glutamatergic modulation, synaptic plasticity, and neuroprotection against ischemic damage. Our product achieves superior 99%+ purity, ensuring consistent results in memory impairment models, antihypoxic assays, and neurotransmitter enhancement investigations. Crafted through precise amidation processes in controlled facilities, this white to off-white crystalline powder facilitates accurate dosing in preclinical protocols, making it essential for dissecting AMPA/NMDA receptor interactions and cognitive metabolism without impurity-related artifacts.

Physical and Chemical Properties:

• Form: White to off-white crystalline powder
• Purity: ≥99% (validated by HPLC, NMR, and MS)
• Molecular Formula: C₁₁H₁₂N₂O₆
• Molecular Weight: 268.23 g/mol
• Solubility: Good solubility in water (>10 mg/mL); soluble in DMSO and ethanol; sparingly soluble in non-polar solvents
• Appearance: Fine, odorless crystalline solid
• CAS Number: 112193-35-8
• Storage: Store at room temperature (15-25°C) in a desiccator; protect from light and humidity to preserve stability

This powder’s aqueous solubility supports seamless integration into in vitro and in vivo experiments, enhancing reproducibility in behavioral and electrophysiological studies. Buy Nooglutyl today for reliable 99% pure Nooglutyl in your Nooglutyl for research initiatives.

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Introduction

In the burgeoning field of cognitive neuroscience and nootropic pharmacology, Nooglutyl emerges as a compelling synthetic agent with profound implications for understanding brain resilience and memory dynamics. Developed in the 1980s at the Research Institute of Pharmacology, Russian Academy of Medical Sciences, Nooglutyl – chemically N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid – represents a fusion of L-glutamic acid and 5-hydroxynicotinic acid, structurally akin to picamilon but with distinct glutamatergic affinities. Its development stemmed from efforts to combat amnesia and cognitive deficits, evolving into a versatile tool for probing neuroprotective mechanisms amid hypoxic and ischemic challenges.

For researchers dedicated to Nooglutyl for research, our 99%+ pure Nooglutyl provides the unyielding quality demanded by intricate assays. Buy Nooglutyl to harness a compound that not only bolsters acetylcholine release for enhanced learning but also fortifies neuronal communication via AMPA and NMDA receptor modulation. This reagent transcends conventional nootropics, offering a scaffold for unraveling energy metabolism in the brain and synaptic fortification, thereby fueling paradigm shifts in treatments for age-related cognitive decline and trauma-induced impairments.

Key Features & Benefits

Nooglutyl is meticulously engineered to satisfy the exacting criteria of progressive research laboratories, amalgamating chemical supremacy with pragmatic enhancements that expedite workflows and uphold discretion.

Key Features:

• Elite 99%+ Purity: Exhaustive purification surpasses 99% benchmarks, obviating impurities that could disrupt glutamatergic signaling in sensitive neuronal cultures.
• Research-Ready Powder: Fine crystalline structure ensures facile dissolution, accommodating microgram precision in dosing for behavioral paradigms.
• Neuroprotective Stability: Robust against oxidative stress, maintaining bioactivity in standard lab environs without polymorphic inconsistencies.
• Veiled International Logistics: Vacuum-sealed within unmarked enclosures, guaranteeing 3-7 day global delivery with traceability safeguards.

Benefits for Researchers:

• Impeccable Reproducibility: 99% pure Nooglutyl yields uniform outcomes in antihypoxic models, such as those demonstrating 30-50% amelioration in memory retention post-ischemia.
• Comprehensive Nootropic Scope: Optimized for Nooglutyl for research in synaptic plasticity and anti-amnesic effects, where it outperforms comparators like Nootropil in exploratory efficacy.
• Absolute Discretion: Stealth, plain packaging devoid of indicators preserves project secrecy, channeling resources toward empirical advancement.
• Seamless Global Access: Insured, expedited shipping to Europe, North America, and Asia nurtures transnational partnerships under rigorous compliance.

Procuring our Nooglutyl redefines buy 99% pure Nooglutyl as a keystone of scientific precision, galvanizing your pursuits toward reproducible, transformative insights.

Product Specifications

Nooglutyl is subjected to thorough physicochemical scrutiny employing premier analytical paradigms, furnishing investigators with unequivocal metrics for protocol refinement. The table herein delineates pivotal specifications, authenticated through spectrometric and chromatographic corroboration.

Property	Specification
Chemical Name	N-[(5-Hydroxy-3-pyridinyl)carbonyl]-L-glutamic acid
Synonyms	Nooglutil, ONK-10, N-(5-Hydroxynicotinoyl)-L-glutamic acid
CAS Number	112193-35-8
Molecular Formula	C₁₁H₁₂N₂O₆
Molecular Weight	268.23 g/mol
Form	Crystalline powder
Melting Point	168-172°C (decomposes)
Solubility	>10 mg/mL in water; soluble in DMSO and ethanol
Log P	-1.2 (hydrophilic profile)
pKa	~2.2 (carboxylic), ~9.5 (phenolic)
Boiling Point	Decomposes >250°C
Density	~1.5 g/cm³
Storage Conditions	15-25°C, desiccated, light-protected
Shelf Life	24 months unopened

These hallmarks position Nooglutyl as an exemplary reagent for Nooglutyl for research, interfacing adeptly with GLP-aligned neuropharmacological regimens.

Applications & Usage

Nooglutyl’s glutamatergic orchestration, particularly via AMPA/NMDA potentiation and acetylcholine augmentation, establishes it as a multifaceted instrument in cognitive and neuroprotective research. Pioneering studies from the 1990s, including comparative trials against Nootropil and Pyritinol, affirmed its superiority in reinstating memory post-hypoxia, with rodent models exhibiting up to 40% recovery in passive avoidance tasks. Subsequent inquiries have illuminated its role in BDNF modulation and ischemic neuroprotection, as per Eksp Klin Farmakol publications.

Typical Research Applications:

• Memory and Learning Enhancement: Deployed in scopolamine-induced amnesia paradigms to restore hippocampal synaptic efficacy, aligning with data showing normalized exploratory behavior in SAMP10 senescence models.
• Neuroprotective Investigations: Utilized in cerebral ischemia simulations, mitigating neuronal loss via antihypoxic cascades, consistent with 20-30% BDNF elevation in cortical slices per OECD 425 guidelines.
• Glutamatergic Pathway Studies: Probes AMPA receptor trafficking in organotypic cultures, supporting glutamate homeostasis without excitotoxicity, under ARRIVE-compliant designs.
• Cognitive Metabolism Research: Assesses acetylcholine-glutamate crosstalk in forced alternation tasks, revealing amplified focus metrics in aged cohorts.
• Anti-Aging Brain Models: Explores longevity extensions in accelerated aging mice, contributing to nootropic hierarchies for vigilance and retention.

In application, reconstitute Nooglutyl in sterile water to 1-10 mM stocks, titrating to 5-30 mg/kg IP for rodents or 10-50 μM in neuronal assays. Observe EU Directive 2010/63/EU ethical imperatives, integrating humane endpoints for ethically sound, high-caliber data. This polyvalence substantiates 99% pure Nooglutyl as a vanguard in innovative Nooglutyl for research frameworks.

Purity & Testing

Purity constitutes the linchpin of neuroscientific credibility, and our Nooglutyl attains ≥99% – a sine qua non for AMPA affinity assays where contaminants could engender 15-25% discrepancies in synaptic potentiation.

Rigorous Testing Procedures:

• High-Performance Liquid Chromatography (HPLC): Reverse-phase methodology with UV at 254 nm delineates impurities to <0.1%, screening nicotinic byproducts per USP <621>.
• Nuclear Magnetic Resonance (NMR): ¹H/¹³C profiling verifies the hydroxy-pyridinyl-glutamyl amide, with signature shifts at 8.5 ppm (aromatic) and 4.2 ppm (α-methine) matching referential spectra.
• Mass Spectrometry (MS): ESI-MS/MS authenticates [M-H]⁻ at m/z 267, fragmenting to confirm carbonyl linkages sans decarboxylation relics.

Implemented per ICH Q3A(R2) and EP 2.2.46 tenets, these engender batch COAs, augmenting provenance. Concretely, this 99%+ purity attenuates variability in BDNF induction by 20%, trumping subpar alternatives. Championing our accredited buy 99% pure Nooglutyl endows your endeavors with the probative sinew for peer-vetted epiphanies.

Safety & Handling Guidelines

Laboratory prudence is inviolable, and Nooglutyl is outfitted with precepts to traverse its benign profile while reinforcing its research-only edict. As a glutamyl amide, it evinces scant acute hazards yet invites prosaic mitigations against ocular or dermal ingress.

Handling Instructions:

• PPE Directives: Avail nitrile gloves, protective lenses, and smocks; execute in biosafety cabinets to forestall dust.
• Remediation Tactics: Absorb effusions with cellulose, dilute via aqueous rinse, and inter as non-hazardous per OSHA protocols.
• Conservation: Enclose in desiccated amber at 15-25°C; shun extremes precipitating hydrolysis.
• Reactivity Insights: Amicable with buffers; antipathetic to oxidants cleaving the phenolic moiety.

Disclaimer: Nooglutyl is vouchsafed for in vitro/ex vivo scrutiny solely. Proscribe human/animal ingestion, therapeutics, or diagnostics. SDS deems it non-toxic (GHS Category 5), albeit proxies suggest ephemeral GI flux. Invoke biosafety adjudication to temper perils, assuring Nooglutyl for research with impeccable rectitude.

Global Shipping & Discreet Delivery

Exploration eclipses confines, and our stalwart logistics lattice conveys Nooglutyl to 140+ dominions with dispatch and dissimulation. Foresee 2-5 day European consummation, 4-8 days transoceanic, buttressed by telemetry and aegis.

Discreet Delivery Protocols:

• Banal Facades: Remitted in innocuous satchels emulating mundane missives – sigil-free, intimation-nil.
• Vacuum Bastion: Bi-sealed, desiccant-laden sheaths repel maceration and incursion, armored for empyrean trials.
• Cryptic Recitals: Dockets invoke “pedagogic adjuncts,” eluding nomenclature to expedite fiscal gauntlets.
• Vicissitude Shields: Ambient bolsters obviate chilling, conserving crystallinity athwart transit.

This pall of obscurity girds your quest, metamorphosing buy Nooglutyl into an unheralded vein of sagacity. Our 99.5% fidelity narrates a nexus hewn for sapient urgencies.

Why Choose Us?

Amid the nootropic bazaar, we loom as the apotheosis of constancy, velocity, and lore – virtues annealed o’er 13 years confederating with apical academes.

• Alacritous Rendition: Immediate assay with elite conduits for juncture mandates.
• Impregnable Shroud: Spotless evasion annals, through esoteric veiling ruses.
• Erudite Phalanx: Perpetual, enshielded parleys with nootropic savants schooled in glutamyl arcana.
• Purity Patrimony: A saga of 99% pure Nooglutyl tenders, hallowed by GLP sentinels and plaudits.

Our compact transcends vendition; it’s a pact magnifying Nooglutyl for research toward cosmological cognitions.

Legal & Safety Disclaimer

Nooglutyl is proffered exclusively for ratified laboratory catechism in circumscribed realms. It garners no fiat from FDA, EMA, or peers for human/veterinary ingress, interdicting ingestion, inhalation, or tegumental transit. Pactees must transcend 18 orbits, attesting fealty to regnant edicts on probative media. As of October 2025, it persists unscheduled in the US (DEA) and EU (non-REACH for R&D stipends), albeit hazarding unvetted conveyance.

Transgressions summon forensic retorts. We exhort congress with ethic conclaves and legates for consonance. Preeminent: Heed SDS dogmas for jeopardy easement, decreeing graduated inquests. Dispensation circumscribes our ambit – perspicacious curation, the catechist’s for judicious 99% pure Nooglutyl husbandry.

FAQ Section

What is Nooglutyl used for in research? Nooglutyl is instrumental in nootropic and neuroprotective research for interrogating glutamatergic enhancement and memory restitution. It undergirds paradigms in hypoxic amnesia and synaptic fortification, proffering illuminations on acetylcholine-glutamate synergy sans excitotoxic liabilities, harmonious with 1980s-2000s Russian pharmacopeia.

Is Nooglutyl legal? Nooglutyl abides unscheduled in the US (DEA October 2025) and EU bailiwicks, devoid of therapeutic seal. Acquirers traverse ingress canons and avow laboratory singularity. As of October 16, 2025, it burgeons in inquisitorial crevices for Nooglutyl for research, enjoining locale-specific exactitude.

How discreet is the shipping? Sublimely cloaked: Remittances array mundane integuments, vacuumed entrails sans epithets, and recitals hinting “erudite paraphernalia.” Our liturgy assures immaculate ingress, ferrying buy Nooglutyl spherically incognito.

What is the purity level? ≥99% purity is inexorable, vaulting canons to tender immaculate 99% pure Nooglutyl for catechisms untainted by interlopers.

How is purity tested? Through HPLC for elution taxonomy, NMR for amidic ratification, and MS for ionic avowal – synoptic rigors per ICH axioms, engendering COAs girding Nooglutyl for research authenticity.

What are storage recommendations for Nooglutyl? Ambient (15-25°C) in desiccated umbra, forestalling phenolic oxidation to uphold 24-month vigor, priming 99% pure Nooglutyl for perennial catechism.

Can Nooglutyl be used in neuroprotective models? Affirmative, at 5-30 mg/kg PO in rodent ischemia proxies for BDNF augmentation, consonant with ARRIVE canons, emphasizing humane sentinel oversight.